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Research objectives

This project aims to answer the following research questions:

  1. Q1 Knowing that some patients recover sooner and some later after cataract surgery, what are the markers of delayed tear film recovery?
    • Can we describe the tear film characteristics that predict the prolonged dry eye symptoms after cataract surgery?
  2. Q2 Can the iatrogenic, transient form of dry eye disease (DED) caused by CS be used as a research platform to study the changes in the ocular surface and tear film parameters that occur in non-iatrogenic DED?
  3. Q3 Could the post-cataract group provide valuable and hitherto unavailable information on the underlying pathology involved in non-iatrogenic DED, where the starting point is impossible to record?
  4. Hence, the aim of this collaborative research project is to develop reliable methodologies for supporting diagnosis and assessment of DED focused on differencing the tear film sublayer’s quality. This will be achieved by comprehensive investigating the physiology of the ocular surface and tear film, using traditional and experimental techniques in a longitudinal research scenario in which DED is induced (iatrogenically, via cataract surgery) and managed.